Day 2 :
Keynote Forum
Sergey Suchkov
I.M. Sechenov First Moscow State Medical University, Russian Federation
Keynote: Predictive, preventive and personalized medicine (PPPM) as an upgraded model of national and international healthcare services to secure a future of clinical research and practice
Time : 09:00-09:30
Biography:
Sergey Suchkov is a Researcher-Immunologist, a Clinician graduated from Astrakhan State Medical University, Russia in 1980. He has been trained at the Institute for Medical Enzymology, The USSR Academy of Medical Sciences, National Center for Immunology (Russia), NIH, Bethesda, USA and British Society for Immunology to cover 4 British university facilities. Since 2005, he has been working as Faculty Professor of I.M. Sechenov First Moscow State Medical University and of A.I. Evdokimov Moscow State Medical & Dental University. He is the First Vice-President and Dean of the School of PPPM Politics and Management of the University of World Politics and Law. He was a Scientifi c Secretary-in-Chief of the Editorial Board of the International Journal “Biomedical Science” (Russian Academy of Sciences and Royal Society of Chemistry, UK) and The International Publishing Bureau at the Presidium of the Russian Academy of Sciences. He was a Director of the Russian-American Program in Immunology of the Eye Diseases. He is a Member of EPMA, NY Academy of Sciences and an Editorial Board Member for Open Journal of Immunology and others.
Abstract:
Predictive, Preventive and Personalized Medicine (PPPM) as the Healthcare Model of the near future, as well as its associated tool, i.e., Translational Medicine (TraMed), represent an innovative model of healthcare services to consolidate advanced healthcare and robust platform for relevant industrial branches of predictive diagnostics, personalized therapeutics and preventive drugs. To achieve the implementation of PPPM concept into the practice, it is necessary to create a fundamentally a new strategy based upon the subclinical recognition of biomarkers long before the disease clinically manifests itself. Th is strategy would give a real opportunity to secure preventive measures whose personalization could have a signifi cant infl uence on demographics! Meanwhile, penetration of new technologies into the market would demand the implementation of reforms not only in the area of healthcare, but in medical education as well. Th erefore, the problem of the preparation of specialists of the newest generation to secure priority in growing up medical doctors as creative artists, is becoming particularly urgent and would require signifi cant revision of training programs and curricula of the higher education as applicable to the medical schools. Modernization and integration of widely accepted medical and teaching standards require consolidation of both the natural (life) sciences and medicine that may become the conceptual basis for the medical school curricula. The main goal of this training is not simply to achieve advanced training and expansion of technological skills, but to provide development of novel multifaceted approaches to build academic schools of the newest generations and to thus outline curricula and courses to suit markets of the newest medical platforms. PPPM consists of a wide variety of tests and tools including so much complicated areas as networking, mathematic modeling, nanotools and nanotechnologies, cloudy and mobile technologies to suit the requests and standards of the new healthcare model. Coordinated measures to optimize the progress should be well-focused on solving the accumulating problems in healthcare and the concomitant economic burden that societies across the globe are facing more and more. Taking into consideration the current trends and personal experience, we have made fi rst steps towards direct involvement in the modernization of the healthcare model. Group and individual vectors as part of the basic inventory are represented by translational medicine, bioinformatics, drug design, translational tools and regulatory courses). Our model for accelerated development of continuous vocational education (CVE) in the sphere of PPPM and TraMed is based on the combinatorial approaches (competence, module-type approach, personal activity, program-design and problem-oriented) to the elucidation of innovative processes of modernization of the existing educational model. Th e application of the accelerated model for development of CVE has required a new type of the infrastructure of the Curricula. PPPM whilst secured by the upgraded educational system would off er great and real promise for the future. And the next generations will speak about the XXI century as a time, when healthcare services became predictive and preventive and its outcomes secured and guaranteed!
Keynote Forum
Moorkath Nandakumaran
University of Kuwait, Kuwait
Keynote: Maternal-fetal transport of L-leucine in pre-eclamptic pregnancies in vitro
Time : 09:30-10:00
Biography:
Moorkath Nandakumaran Obtained Doctorate Degree in Reproductive Physiology from University of Paris VI in the year 1979 and later did post-doctoral training as a Research Consultant for about 4 years at the famous St Vncent de Paul Hospital, Paris in fi eld of Biochemical Pharmacology. He is currently Professor in Obstetrics &Gynecology Depoartment of Kuwait medical Faculty, Kuwait University. Dr Nandakumaran specializes in research relating to maternal-fetal exchange of nutrients and drugs in control and disease state including pre-eclampsia and diabetes mellitus , using isolated human placental perfusion technique as well as using experimentally induced diabetic rats. Has published nearly 100 research papers and presentations in international scientifi c journals and conference proceedings and has been Invited Speaker in many International Conferences.
Abstract:
Introduction: Previous reports from our laboratory had shown that maternal-fetal transport kinetics of model nutrients and reference markers were altered in toxemia model placenta in vitro. Th is study was meant to explore whether transport kinetics of a model amino acid L-Leucine were altered in placenta from pre-eclamptic pregnancies in vitro. Methods: Human placenta from pre-eclamptic pregnancies were collected post-partum.14-C labeled L-leucine (specifi c activity: 54 uCi/mmol, Amersham, UK) along with tritiated water (specifi c activity 5 mCi/mmol, Amersham, UK) as reference marker were then injected as a single bolus (100 ul) into the maternal arterial circulation of perfused placental lobules and perfusate samples collected from maternal and fetal circulations over a period of 5 minutes. National Culture and Tissue Collection medium, diluted with Earle's buff ered salt solution was used as the perfusate. Concentration of labeled substances in perfusate samples in control and toxemia model perfusion phases was assessed by scintillation spectrometry (LKB Wallac Scintillation Spectrometer, Denmark) using preadjusted double window counting. Transport kinetics of substances studied was computed using established permeation parameters. Results: Diff erential transport rates of L-leucine and tritiated water in 8 perfusions diff ered signifi cantly (Student's t-test; p<0.05) for all transport fractions studied in control perfusions and perfusions from three pre-eclamptic pregnancies. Transport Fraction index of L-leucine compared to reference marker averaged 35.2% in control perfusions (n=8) and 22.20% in perfusions from pre-eclamptic pregnancies (n=3) respectively. Th e diff erence observed in TF index of L-leucine in control and study groups was statistically signifi cant (Student's t-test, p<0.05) Indices of transport fraction and certain pharmacokinetic parameters such as area under the curve, absorption rate, elimination rate of deoxy glucose compared to reference marker were signifi cantly diff erent (p<0.05) between control and pre-eclampsia groups. Absorption rate: Elimination rate indices of model amino acid diff ered signifi cantly between control and study groups (Student's t-test; p<0.05). Conclusions: Our studies show for the fi rst time that transport behavior of a model amino acid leucine is compromised in preeclamptic pregnancies and that the altered behavior of placental membrane in amino acid transport in such pregnancies has the potential to cause undesirable sequelae for the fetus and neonate.
- Case Reports: Obstetrics and Gynecology | Gastroenterology | Pulmonology | Dentistry Epidemiology | Public Health | Pediatrics | Cancer Science
Session Introduction
Sergey Suchkov
I.M. Sechenov First Moscow State Medical University, Russian Federation
Title: Predictive, preventive and personalized medicine (PPPM) as an upgraded model of national and international healthcare services to secure a future of clinical research and practice
Time : 09:00-09:30
Biography:
Sergey Suchkov is a Researcher-Immunologist, a Clinician graduated from Astrakhan State Medical University, Russia in 1980. He has been trained at the Institute for Medical Enzymology, The USSR Academy of Medical Sciences, National Center for Immunology (Russia), NIH, Bethesda, USA and British Society for Immunology to cover 4 British university facilities. Since 2005, he has been working as Faculty Professor of I.M. Sechenov First Moscow State Medical University and of A.I. Evdokimov Moscow State Medical & Dental University. He is the First Vice-President and Dean of the School of PPPM Politics and Management of the University of World Politics and Law. He was a Scientifi c Secretary-in-Chief of the Editorial Board of the International Journal “Biomedical Science” (Russian Academy of Sciences and Royal Society of Chemistry, UK) and The International Publishing Bureau at the Presidium of the Russian Academy of Sciences. He was a Director of the Russian-American Program in Immunology of the Eye Diseases. He is a Member of EPMA, NY Academy of Sciences and an Editorial Board Member for Open Journal of Immunology and others.
Abstract:
Predictive, Preventive and Personalized Medicine (PPPM) as the Healthcare Model of the near future, as well as its associated tool, i.e., Translational Medicine (TraMed), represent an innovative model of healthcare services to consolidate advanced healthcare and robust platform for relevant industrial branches of predictive diagnostics, personalized therapeutics and preventive drugs. To achieve the implementation of PPPM concept into the practice, it is necessary to create a fundamentally a new strategy based upon the subclinical recognition of biomarkers long before the disease clinically manifests itself. Th is strategy would give a real opportunity to secure preventive measures whose personalization could have a signifi cant influence on demographics! Meanwhile, penetration of new technologies into the market would demand the implementation of reforms not only in the area of healthcare, but in medical education as well. Th erefore, the problem of the preparation of specialists of the newest generation to secure priority in growing up medical doctors as creative artists, is becoming particularly urgent and would require signifi cant revision of training programs and curricula of the higher education as applicable to the medical schools. Modernization and integration of widely accepted medical and teaching standards require consolidation of both the natural (life) sciences and medicine that may become the conceptual basis for the medical school curricula. Th e main goal of this training is not simply to achieve advanced training and expansion of technological skills, but to provide development of novel multifaceted approaches to build academic schools of the newest generations and to thus outline curricula and courses to suit markets of the newest medical platforms. PPPM consists of a wide variety of tests and tools including so much complicated areas as networking, mathematic modeling, nanotools and nanotechnologies, cloudy and mobile technologies to suit the requests and standards of the new healthcare model. Coordinated measures to optimize the progress should be well-focused on solving the accumulating problems in healthcare and the concomitant economic burden that societies across the globe are facing more and more. Taking into consideration the current trends and personal experience, we have made fi rst steps towards direct involvement in the modernization of the healthcare model. Group and individual vectors as part of the basic inventory are represented by translational medicine, bioinformatics, drug design, translational tools and regulatory courses). Our model for accelerated development of continuous vocational education (CVE) in the sphere of PPPM and TraMed is based on the combinatorial approaches (competence, module-type approach, personal activity, program-design and problem-oriented) to the elucidation of innovative processes of modernization of the existing educational model. Th e application of the accelerated model for development of CVE has required a new type of the infrastructure of the Curricula. PPPM whilst secured by the upgraded educational system would off er great and real promise for the future. And the next generations will speak about the XXI century as a time, when healthcare services became predictive and preventive and its outcomes secured and guaranteed!
Moorkath Nandakumaran
University of Kuwait, Kuwait
Title: Maternal-fetal transport of L-leucine in pre-eclamptic pregnancies in vitro
Time : 09:30-10:00
Biography:
Moorkath Nandakumaran Obtained Doctorate Degree in Reproductive Physiology from University of Paris VI in the year 1979 and later did post-doctoral training as a Research Consultant for about 4 years at the famous St Vncent de Paul Hospital, Paris in fi eld of Biochemical Pharmacology. He is currently Professor in Obstetrics &Gynecology Depoartment of Kuwait medical Faculty, Kuwait University. Dr Nandakumaran specializes in research relating to maternal-fetal exchange of nutrients and drugs in control and disease state including pre-eclampsia and diabetes mellitus , using isolated human placental perfusion technique as well as using experimentally induced diabetic rats. Has published nearly 100 research papers and presentations in international scientifi c journals and conference proceedings and has been Invited Speaker in many International Conferences.
Abstract:
Introduction: Previous reports from our laboratory had shown that maternal-fetal transport kinetics of model nutrients and reference markers were altered in toxemia model placenta in vitro. Th is study was meant to explore whether transport kinetics of a model amino acid L-Leucine were altered in placenta from pre-eclamptic pregnancies in vitro. Methods: Human placenta from pre-eclamptic pregnancies were collected post-partum.14-C labeled L-leucine (specifi c activity: 54 uCi/mmol, Amersham, UK) along with tritiated water (specifi c activity 5 mCi/mmol, Amersham, UK) as reference marker were then injected as a single bolus (100 ul) into the maternal arterial circulation of perfused placental lobules and perfusate samples collected from maternal and fetal circulations over a period of 5 minutes. National Culture and Tissue Collection medium, diluted with Earle's buff ered salt solution was used as the perfusate. Concentration of labeled substances in perfusate samples in control and toxemia model perfusion phases was assessed by scintillation spectrometry (LKB Wallac Scintillation Spectrometer, Denmark) using preadjusted double window counting. Transport kinetics of substances studied was computed using established permeation parameters. Results: Diff erential transport rates of L-leucine and tritiated water in 8 perfusions diff ered signifi cantly (Student's t-test; p<0.05) for all transport fractions studied in control perfusions and perfusions from three pre-eclamptic pregnancies. Transport Fraction index of L-leucine compared to reference marker averaged 35.2% in control perfusions (n=8) and 22.20% in perfusions from pre-eclamptic pregnancies (n=3) respectively. Th e diff erence observed in TF index of L-leucine in control and study groups was statistically signifi cant (Student's t-test, p<0.05) Indices of transport fraction and certain pharmacokinetic parameters such as area under the curve, absorption rate, elimination rate of deoxy glucose compared to reference marker were signifi cantly diff erent (p<0.05) between control and pre-eclampsia groups. Absorption rate: Elimination rate indices of model amino acid diff ered signifi cantly between control and study groups (Student's t-test; p<0.05). Conclusions: Our studies show for the fi rst time that transport behavior of a model amino acid leucine is compromised in preeclamptic pregnancies and that the altered behavior of placental membrane in amino acid transport in such pregnancies has the potential to cause undesirable sequelae for the fetus and neonate.
Deanne S Saores
Royal Prince Alfred Hospital, Sydney, Australia
Title: Papillary Renal Cell Carcinoma Seeding Along a Percutaneous Biopsy Tract
Time : 10:00-10:20
Biography:
Deanne Soares is a senior surgical resident at Concord Repatriation General Hospital in Sydney, Australia. She has completed a Masters of Surgery from The University of Sydney and a Masters of Health Leadership and Management from the University of Wollongong. She is currently engaged in multiple research projects in the fields of surgery and training and education
Abstract:
The use of percutaneous biopsies is useful in the diagnosis and management of renal masses with a complication rate of <0.01%. However, a potential hazard of this is tract tumor seeding but this is so rare in renal cell carcinoma (RCC) that its frequent use in the assessment of indeterminate renal masses has been justified. We report a case of tumor seeding caused by percutaneous biopsy of a papillary renal cell carcinoma detected on pathological assessment of the partial nephrectomy specimen in a 50-year-old male. Literature review found that up until 1991, there were only 5 reported cases of RCC tract seeding and in 2013 there were a further 3 cases reported. In general, tract seeding will relate to the amount of disruption of the tumor capsule (needle caliber, number of punctures), pressure of egress at the puncture site (for example, cystic masses or escaping hematoma), whether tumor cells are dropped from the needle on its withdrawal (failure to maintain negative pressure, burred needle tip) and the ability of tumor cells to survive when deposited into a scar. This is one of only a few contemporary case reports of RCC seeding along a percutaneous biopsy tract. Whilst this complication is so rare that it does not warrant a need to cease the use of percutaneous biopsy of renal masses, it certainly highlights the possibility of tract seeding as a potential hazard. As such, certain considerations such as appropriate patient selection, the use of correct equipment and suitable biopsy technique, should be made to minimize the risk of this complication.
Mahmoud Shafei
Ain shams University, Egypt
Title: Extraordinary case of perforated meckel’s diverticulum with a pathological abruptness of GIST (Gastrointestinal stromal tumor) in 74 years old man
Time : 10:20-10:40
Biography:
Mahmoud El-Shafei has completed his MD degree in General Surgery, Faculty of Medicine, Ain Shams University (1994) and completed the ISO Training course-Quality system documentation-Atlantic Engineering-Management Academy (AEMA). He is currently working as a Professor of General and Laparoscopic Surgery, Ain Shams University, Egypt. He is also a Consultant of General, Laparoscopic & Oncosurgery in Ain Shams Specialized Hospital & Eldemerdash University Hospital. He is a Visitor Consultant of General, Laparoscopic & Oncosurgery, Shobra Health Insurance Hospitals and General Transportation Hospitals from 2006 to till date.
Abstract:
A Meckel’s diverticulum is a vestigial remnant of the omphalomesenteric (vitello-intestinal) duct. As a congenital anomaly, it is a true diverticulum that includes all three coats of the small intestine. Generally, a Meckel diverticulum ranges from 1 to 12 cm in length and is found 45-90 cm proximal to the ileocecal valve. It frequently contains heterotropic tissue; when it does, gastric mucosa accounts for 50%. It is no exaggeration to say that tumors within Meckel’s diverticulum are very uncommon with particular concern to GIST which is very rare finding. Fortunately we reported a case of 74 years old man with acute right iliac fossa pain and shock. On examination the patient had tachycardia and hypotension with tenderness and rebound tenderness in the hypogastrium suggestive of pelvic peritonitis. Chest X ray revealed air under diaphragm, ultrasound abdomen showed right iliac fossa mass. Diagnosis of perforated hollow organ was established. After rapid resuscitation, he was operated on via a lower midline incision and surprisingly we found perforated tumor mass in Meckel’s diverticulum. We resected the Meckle’s divertivculum containing the mass with 4 cm of small bowel on either side and primary restoration of bowel continuity was done. Histopathological assessment of the mass confirms GIST. According to our analysis we recommend all surgeons to consider tumors of Meckel’s diverticulum as one of differential diagnosis of intra-abdominal neoplasms.
Samar Abbas
St. Luke’s Hospital, Ireland
Title: Familial early onset paget’s disease: A case report
Time : 10:40-11:00
Biography:
Dr. Samar Abbas Jaffri, born in 31st August 1984, in Karachi Pakistan, did my primary schooling in Brooklyn secondary school karachi, did my SSC examination from gulistan school karachi in 2000, did my HSC examination in 2002 from DJ sindh Government science college karachi, recieved my primary medical education from baqai medical university up til 2008. I joined Jinnah Postgraduate Medical centre in 2009 did my internship over there for 1 year, entered in FCPS (Pak)/MRCP(UK) training program Medical Unit II, (Ward 6), Jinnah Postgraduate Medical Centre Karachi, Pakistan in 2011, completed my UK membership in 2015, Joined St. Lukes Hospital Ireland in July 2014 as Medical Registrar, being promoted to Cardiology Registrar in July 2015
Abstract:
Introduction: Familial Early - Onset of Paget’s Diseases is an Autosomal dominant disorder associated with Mutation in gene TNFRSF11A which encode the Receptor Activator of Nuclear Factor Kappa (RANK).It is rare in Asians and usually presents in teens or twenties. Its features are similar to those of the classic form of the disease, although it is more likely to affect the skull, spine, and ribs (the axial skeleton) and the small bones of the hands. The serum alkaline phosphatase urinary hydroxyproline and serum C- telopeptide are elevated. Case We report a case of 21 years old boy who presented with complain of generalized bone pain for 12years, multiple bone fractures on slight trauma leading to progressive bone deformities for 5years and gradual hearing Loss for 4 years. His parents are cousins and one of their cousin had a similar problem but she died undiagnosed at 40.Patient‘s younger sister (20years) has similar problem since the age of 10 yrs. On investigation his CBC, UCE, LFTs , Uric acid, Ca, PO4, PTH, vit D3 levels were all normal, but his Alkaline phosphatase was markedly elevated at 2526 U/L (100 – 290).His sister also had similar laboratory results. His bone biopsy was consistent with Familial early – onset paget ‘s disease. Conclusion: Familial Early onset Paget's disease is a rare disease in Asians and usually presents in young age in which alkaline phosphatase is markedly raised, confirmation of diagnosis is by bone biopsy and gene studies, in our case we were unable to do genetic studies because of lack of funding, and Treatment of choice is bisphosphonates. Long-term follow-up is mandatory in these patients in order to identify and treat any subsequent complications
Noha Behairy
Cairo University, Egypt
Title: Diagnostic value of MRI in fetal urinary tract anomalies
Time : 11:15-11:35
Biography:
Noha Behairy is working as a Professor of Radiology, Radiology Department, Cairo University. She is the reviewer for the European Radiology Journal, Journal of Radiology case reports, Egyptian Journal of Radiology and Nuclear Medicine
Abstract:
Objective: To evaluate the contribution of adding MRI findings to sonographic data when assessing fetal urinary tract anomalies and to determine how this addition may affect the management of pregnancy. Methods: We examined 26 fetuses with sonographically suspected congenital urinary tract anomalies by 2D/3D ultrasound, Doppler and MRI. The gestational age range was 18-36 weeks. 40% of the women were in the second trimester while 60% were in their third trimester. The diagnosis was confirmed by postnatal ultrasound in born babies and autopsy in still born or aborted fetuses. Results: We found different urinary tract anomalies. MRI changed the US diagnosis in 6 cases and added information in 5 cases, hence changing the patient’s management in 34.6% of cases. MRI confirmed US diagnosis in 16 fetuses. Ultrasound was superior to MRI in one case of renal failure. Associated extra renal anomalies were detected in ten cases (38.4%). 13 lethal renal anomalies were included in this study. The diagnosis was confirmed by postnatal US or CT in viable babies and autopsy in still birth or aborts. Conclusion: Fetal MR imaging should be used as a complementary modality to US in diagnosing fetal urinary abnormality in which US findings are inconclusive or equivocal.
Mohamed Touni
Nasser Institute Hospital, Egypt
Title: Marcus Gunn Syndrome “Jaw Winking Phenomenon†. based on a case report
Time : 11:35-11:55
Biography:
Mohamed Touni has completed his Dental degree from Ain Shams University (Egypt), and then he attached to a 5 years residency in oral and maxillofacial surgery at Nasser institute hospital. He has a very good log book and he has done and assisted in many surgeries. He has a lot of experience in the fields of trauma, orthognathic surgeries and computer guided surgeries. He has done a lot of presentations and has 3 case reports in progress and other type of publish.
Abstract:
Life threatening infection of odontogenic origin may extend to potential spaces formed by fascial planes of lower head and upper cervical area. The incidence of these space infections has been gradually reduced by modern antibiotic therapy. Sublingual hematoma is a rare complication usually seen after oral anticoagulant use. Sublingual hematoma secondary to deep neck infection is rare unpreviously reported before. Review of literature didn’t reveal any case reports of sublingual hematoma following deep neck infection of fascial spaces. A case of deep neck infection of odontogenic origin with subsequent sublingual hematoma with ultimate fatal outcome will be described in this conference.
Amer Al Ani
Sheikh Khalifa Hospital, KSA
Title: Testicular seminoma invading the dudenum. misdiagnosed as duodenal tumor. A case report
Time : 11:55-12:15
Biography:
Amer Hashim Hassan Al Ani has graduated from Baghdad Medical School. He has completed his Arab Board in General Surgery (2000), GIT Surgery subspecialty (2005), FRCS from The Royal College of Physician and Surgeon Glasgow (2011). He is currently a GIT & General Surgeon in Department of General Surgery of Sheikh Khalifa Hospital, UAE. He has published more than 15 papers in reputed journals and has been serving as an article Review Member of reputed journals. He has participated as speaker in more than 35 national and international conferences.
Abstract:
Testicular cancers are the most common malignancies in men aged 15-35 years. Their incidence constitutes 0.8% of all men cancers worldwide, with a mortality rate of 0.1%. Testicular malignancies rarely metastasize to the retroperitoneum and involve upper gastrointestinal tract. Complications like intestinal obstruction, hemorrhage and ulceration of bowel mucosa are usually present. . We report here a 30 year old man presented with severe anemia due to upper gastrointestinal bleeding from ugly duodenal growth diagnosed by endoscopy. Biopsy revealed a moderately differentiated adenocarcinoma of the duodenum. The patient was referred to our unit for possible surgery (Whipple’s procedure). A thorough examination documented left testicular masses, slide review and immune stains showed duodenal metastatic lesion from a testicular germ cell tumor. Patient was treated by left orchidectomy (biopsy showed seminoma) and chemotherapy. One year later no gastrointestinal complaints or anemia were detected and patient was overweight. Following completion of chemotherapy, endoscopy showed no evidence of tumor in duodenum. CT scan abdomen showed normal retroperitoneum.
Adel M Mishriky
Professor, Suez Canal University, Egypt
Title: Teachers’ awareness of learning difficulties in primary school children in Al-abnaa schools, Saudi Arabia
Time : 12:15-12:35
Biography:
Adel M Mishriky has graduated from Ain-Shams University Medical School, Egypt in 1976 and completed his Doctoral degree in Occupational Medicine in a joint program between the University of California at Los Angeles (UCLA) and Suez Canal University (SCU) in Egypt. She has completed her Postdoctoral studies at London School of Hygiene and Tropical Medicine. He was the Chairman of the Department of Community Medicine at the Faculty of Medicine, SCU, and he is currently an Emirates Professor. He has published more than 60 papers in reputed journals and has been serving as the Editorial Board Member of Saudi Medical Journal
Abstract:
Learning difficulties (LD) are hard for the public to understand and for educators to treat. This study aim is to contribute to improvement of the learning difficulties problem in primary schools in Saudi Arabia through measuring the awareness of primary school teachers of this problem, its identification and the role of teachers and describing its teachers’ reported prevalence. A cross sectional study design was used in this study carried out at Al-abnaa schools (boys and girls) in Riyadh city on a sample of 200 teachers. Data collection was through a self administered questionnaire to assess awareness of the term: “Learning Difficulties” (LD), its definition, causes, manifestation in reading, writing and math associated socio behavioral problems and the role of the teacher. The response rate was 73%. According to teachers’ opinions, the median of estimated percent of children with LD in their classes was 5.7% with inter quartile range 1.5-10.0%. Most teachers (77.4%) reported being aware of the term LD but only 23.3% could define it and 24% had correct knowledge of its causes. In total, the median score of knowledge was 3 out of a maximum 8 points. Teachers’ knowledge was significantly related to their gender (p<0.001), having a degree in education (p=0.006) and having attended training in LD (p<0.005). In multivariate analysis, female gender and the training courses were the statistically significant independent factors positively influencing the knowledge score. In conclusion, the primary school teachers in the study setting have deficient knowledge regarding learning difficulties, particularly the male teachers. The study recommends such training to all elementary school teachers to be able to early identify cases needing assistance
Nadia H. Rizkalla
Professor, Suez Canal University, Egypt
Title: Pap smear screening in a primary care setting in Saudi Arabia
Time : 12:35-12:55
Biography:
Nadia H Rizkalla has graduated from Cairo University Medical School in 1976 and completed her Doctoral degree in Community Medicine in a joint program between the University of California at Los Angeles (UCLA) and Suez Canal University (SCU) in Egypt. She has completed her Postdoctoral studies at London School of Hygiene and Tropical Medicine. She was the Chairman of the Department of Community Medicine at the Faculty of Medicine, SCU, and she is currently an Emeritus Professor. She has published more than 20 papers in reputed journals and has been serving as WHO Consultant
Abstract:
Objective: To report the findings of an organized Pap smear screening program in a primary care setting and describe the pattern of women’s compliance to screening. Methods: The study was conducted in the Department of Family and Community Medicine at Prince Sultan Military Medical City in Riyadh, Saudi Arabia. The data were the archives of women registered in the Papanicolaou (Pap) smears testing program at the Maternal Care Centers from the start of the program in 2003 to 2010. Results: Of 2184 women, age between 16 and 81 years, 74.1% had their first Pap smear done and 37 (2.4%) had abnormalities. Only 6.7% had their second smear and 5 (3.1%) had abnormalities. Among 23 women who had their third smear, 1 (4.3%) had atypical squamous cells and 1 (4.3%) had Human Papilloma Virus (HPV) changes. In multivariate analysis, woman working status was the most important predictor of her having a Pap smear done along with intake of oral pills and higher parity. Abnormal test finding is predicted by intake of oral contraceptive pills. Conclusion: This study shows low women’s compliance with screening, particularly at the extremes of age and among housewives. Pap smear changes are low and are related to use of contraceptive pills. More effort is needed to increase women's compliance with Pap smear screening guidelines
Vaishali Narayen
Government Dental College and Hospital, India
Title: immunohistochemical labelling of phospho-histone h3 for histoprognostic grading of oral squamous cell carcinomas
Time : 12:55-13:15
Biography:
Vaishali Narayen has completed her Bachelors of Dental Surgery from Rajiv Gandhi University and Masters in Oral Pathology from Dr NTR University of Health Sciences. She is a recipient of gold medal for the best outgoing student in graduation and for securing the 3rd rank in the University in the specialty of Oral Pathology. She is serving as an Assistant Professor of Oral Pathology at Government Dental College and Hospital, Hyderabad, India. She has 5 publications in both national and international journals and has given lectures in various forums.
Abstract:
Background & Objective: The hallmark of oral cancer is excessive proliferation of cells, which is attributed to abnormally increased mitosis. An antibody directed to phosphorylated histone H3 was recently proposed for counting mitotic figures which is one of the most essential factors for determining the histologic grade of OSCC. The aim of the present study was to identify the presence of PHH3 antigens in sections of proven cases of OSCC with immunohistochemistry, also to distinguish mitotic figures from apoptotic bodies and karyorrhectic debris for faster identification and accurate labeling of mitotic figures. Method: 45 tissues of histologically diagnosed cases of OSCC and 10 of normal oral mucosa (controls) were evaluated for the selectivity of H&E and PHH3 immunohistochemical marker. Results: In all the tissues tested with PHH3, mitotic figures were easily detected and the mean number of mitotic figures was highest in PHH3 labeled sections in both the study and control group when compared to H&E. In different grades of OSCC the mean number of mitotic figures using PHH3 was found to be higher in PDSCC as compared with MDSCC and WDSCC. Conclusion: Increased mitotic figures and identification of prophase nuclei with rapid detection of mitotic figures even at low power magnification was possible by PHH3 staining making it a sensitive marker as compared to H&E. PHH3 is a relatively new marker and to the best of our knowledge, no study has been conducted so far to show the correlation between PHH3 mitotic indexing (MI) and recurrence-free survival in a large cohort of oral squamous cell carcinomas.
Sonu Acharya
SOA University, Odisha, India
Title: Platelet concentrates-A viable option for an enviable result
Time : 14:00-14:20
Biography:
Dr. Sonu Acharya completed his BDS in 2003 from the first dental college of India, namely,Dr.R.Ahmed Dental College,Kolkata and completed his Masters (MDS) in Pediatric Dentistry from prestigious Manipal College of Dental Sciences, Manipal in 2006. He is presently working as a Professor in Institute of Dental Sciences, SOA University, India. He is editorial member of American Journal of Public Health, Nigerian Journal of Experimental and clinical biosciences, Journal of Applied dental and medical sciences, Asian Journal of Pharmacy
Abstract:
Development of the bioactive surgical additives is one of the great challenges of clinical research which has been used to regulate inflammation and increase the speed of healing process. Recent scientific development in the concept of tissue engineering has brought about a drastic improvement in the healing response of tissues. Various pathological entities result in dysfunction of the oral tissues and creation of bony defects, thus affecting the quality of life in these patients. The pivotal goal in endodontic, periodontal and maxillofacial tissue regeneration is to reconstruct these defects which led to the search of a bio-fuel. There has always been a focus on devising a “wonder material” that is most effective in its regenerative potential. Various platelet-derived products or platelet concentrates have been introduced that act as biological mediators aiding the healing response. Platelet-rich fibrin (PRF) is one such product that has proved its worth and has edged past the others. The Choukroun’s platelet rich fibrin has opened lot many avenues in the field of dentistry, majorly focusing on the improved healing and regeneration. PRF is a second-generation platelet concentrate widely used to accelerate soft and hard tissue healing and is a strictly autologous fibrin matrix containing a large quantity of platelet and leukocyte cytokines. The basic idea of this paper is to assess the potential use and benefits of Platelet-Rich Fibrin for wound healing and regeneration which are the essence of regenerative dentistry.
Noha Behairy
Cairo University, Egypt
Title: Pena-Shokeir syndrome in three consecutive pregnancies: Prenatal diagnosis by 3D/4D ultrasound, fetal MRI and multislice CT scan
Time : 14:20-14:40
Biography:
Noha Behairy is currently working as a Professor of Radiology, Cairo University, Egypt. She is the Reviewer for the European Radiology Journal, Journal of Radiology Case Reports and Egyptian Journal of Radiology and Nuclear Medicine
Abstract:
The Pena-Shokeir phenotype represents an autosomal recessive syndrome characterized by neurogenic arthrogryposis, facial anomalies and pulmonary hypoplasia. Th is condition was fi rst identifi ed by Pena and Shokeir in 1974 and was subsequently included among the phenotypes associated with the fetal akinesia deformation sequence (FADS). We present a rare case of recurrent Pina-Shokeir syndrome in a 24 year old primigravida and the application of three-dimensional (3D/4D) ultrasonography, fetal magnetic resonance imaging and (3D) multislice computerized tomography in prenatal diagnosis. .
Josaphat Ndelo-di-Phanzu
University of Kinshasa, DR Congo
Title: Surprising unknown H. pylori epidemic in Democratic Republic of Congo (Hp-EDRC)
Time : 14:40-15:00
Biography:
Josaphat Ndelo-di-Phanzu is a Congolese Toxicologist. After completing his graduation as Pharmacist at the Faculty of Pharmacy of the University of Kinshasa in 1975, he moved to Belgium at the Katholieke Universiteit Leuven and obtained Master’s degree in Pharmaceutical Sciences followed by a Doctorate degree in Pharmaceutical Sciences, Branch Toxicology in 1984. He became an Associate Professor in 1986, Professor in 1998 and Ordinary Professor in 2005. Considering the administrative level, he was the Head of the Laboratory of Food and Drug Control of the University of Kinshasa, Head of the Department of Biopharmaceutical Sciences, Vice-Dean of the Faculty of Pharmacy of the University of Kinshasa, Dean of the Faculty of Pharmacy, Rector of the University of Kinshasa and the Head of the Laboratory of Toxicology. He is the President of the Ethics Committee of Central Africa and Vice President of National ethics Committee of DR Congo in the fi eld of ethics of biomedical research.
Abstract:
Since a few decades, numerous suspicions of massive criminal poisonings do exist within the population, in the Democratic Republic of Congo. Th e poison in concern, named “Karuho poison”, is supposed from vegetal or animal origin, located principally in the East region of the country, where the poisoners are also supposed from. According to popular belief, the “Karuho poison” cannot be managed by the modern medicine. Traditional practitioners are recognized as the only specialists of Karuho poisoning. Our research work on “Karuho poisoning” in DR Congo started in 1990. Aft er 20 years of trying, we surprisingly observed in 2010 that, blood specimens from “Karuho poisoning” patients were positive to H. pylori. A poster has been presented at Jackson University, in USA in 2012, on 65 collected blood samples. Since 2012, the number of blood samples has increased signifi cantly with the same positive result concerning the presence of H. pylori. Symptoms presented by the patients, were much diversifi ed, not only digestive but also general and even nervous, indicating a free and massive passage of H. pylori toxin to the blood. About the origin of the H. pylori contamination, we suppose the existence of a natural primary reservoir of the bacterium in the East region of the DR Congo, principally, at or around the Kivu Lake. Th e H. pylori epidemic disease in concern looks like a large opened book, providing to the international scientifi c community an interesting opportunity to learn more about H. pylori infection. Strong international collaboration and suitable fi nancial means are needed for that.
Jignesh Kothari
UN Mehta Institute of Cardiology and Research Centre, India
Title: Excision of multiple cardiac hydatid cysts: A rare clinical entity
Time : 15:00-15:20
Biography:
Jignesh Kothari completed his Medical Graduation (MBBS) from M S University, Baroda in June 1991 and completed Masters of Surgery in the year 1995.He is certifi ed with the Degree of M.Ch. and also DNB from National Board, India in Cardiovascular and Thoracic Surgery in the Year 2001.He later joined as Junior Surgeon at Madras Medical Mission (MMM), Chennai in April 2002 and worked for Year and Quarter. He is currently working at U N Mehta Institute of Cardiology and Research Centre affi liated to B.J.Medical College, Ahmedabad since July 2003 as Assistant Professor (CVTS) and as Associate Professor from May 2013. He is also working as a Post Graduate Teacher for Cardiothoracic and Vascular Specialty in Gujarat University. During this tenure he have operated 6500 cases of various adult cardiovascular surgeries and complicated Cardiac cases as well as Pediatric surgery and vascular surgery independently. He has published 7 research papers in various reputed journals and many complicated cases have also been published in journals.
Abstract:
We herein present a case of successful removal of multifocal, multiple cardiac hydatid cysts: One arising from the left ventricular (LV) postero-lateral wall and another compressing superior vena cava (SVC) & aorta, presented with atypical chest pain in a young male patient. Both the cysts were removed using CPB via midline sternotomy. Superior cyst was removed in mass; while inferior cyst opened, daughter cyst and germinal membrane removed & cavity marsupialized aft er instillation of 3% hypertonic saline as it was densely adhesive to posterior wall of left ventricle (LV). Patient was successfully discharged on 8th post-operative day with albendazole therapy and on regular follow-up without any complications.
Lyubov Chernova
Moscow Regional Clinical Diagnostic Center for Children, Russia
Title: On the verge of a breakthrough in pediatrics
Time : 15:20-15:35
Biography:
Lyubov Chernova graduated from Russian National Research Medical University named after N.I. Pirogov in 2012. She is a Pediatrician at Moscow Regional Clinical Diagnostic Center for Children.
Abstract:
It is now clear that standard protocols for examining pediatric patients do not provide proper level of medical care. Th e latest advances in genomics, proteomics, metabolomics and bioinformatics allow creation of a fundamentally new integrated approach, which applies a ‘predictive, preventive and personalized’ model of care to pediatric practice. Personalized medicine successfully utilizes data obtained from an individual’s genome sequencing. Next generation sequencing has shift ed genetic research from the analysis of separate genes to the parallel studying of hundreds of genes and pathological ways of diseases. Th is same technique provides breakthrough possibilities in molecular diagnostics such as a quick identifi cation of causal mutations, comparative genomic analysis, ability to search for non-random associations between a disease and mutations and identifi cation of new pathological pathways. Th is review, based off of specifi c clinical cases, demonstrates the relevance and practicability of using PPPM concepts in pediatrics. Application of the PPPM approach in pediatrics will help ensure successful prenatal diagnosis of diseases, improve the methods of neonatal screening, promote wider implementation of genetic counseling and develop personalized treatment plans and management of pediatric patients, hence improving prospective results of treatment. Results of such an approach will inevitably lead to a reduction of morbidity and mortality among children. However, the actual question is how to best integrate data obtained from NGS with the personalized medicine approach. Th is question directs us to bioinformatics, which applies high-throughput modeling to support the clinical diagnosis and development of novel treatment strategies in pediatrics.
Rawan Abdul Razack Amir
Medical Student, University of Dammam, Saudi Arabia
Title: Malignant phyllodes tumor of the breast with metastasis to the pancreas: A case report & review of literature
Time : 15:35-15:50
Biography:
Rawan Abdul Razack Amir is a 5th year medical student in the University of Dammam. She had a strong interest in medical literature at a very early stage and had her first publication when she was in her second year of medical school. She currently has a few publications, including a book chapter entitled “Hepatitis C Infection in Kidney Transplantation”, and has many more in the pipeline. She is also very active in raising awareness in her community in a variety of important topics including how to lead a healthy lifestyle, how to live a normal life with chronic diseases, and how to protect from infectious diseases that are constantly on the rise.
Abstract:
Phyllodes tumor is a rare tumor of breast accounting for approximately 1% of all breast neoplasms. Back in 1838, J. Muller coined the term “Cystosarcoma Phyllodes” based on the leaf-like projections of the tumor extending into the cystic spaces and sacromatous stromal growth. However, seeing as up to 70% of all phyllodes tumors are benign, “cystosarcoma” was dropped, and the tumor is now recognized simply as phyllodes tumor. It is mainly seen in females between the ages of 35 and 55. Although most phyllodes tumors are benign, malignant cases do uncommonly occur, 22% of which have distant metastasis typically to the lungs and bones. Rarely, this tumor metastasizes to other locations. Herein we report a case of malignant phyllodes tumor with metastasis to the pancreas. This is a case of a 34 year old woman who presented to the hospital with a large irregular mass of the right breast initially diagnosed to be fibroadenoma. The patient had multiple recurrences which subsequently showed features of malignant phyllodes tumor. Two years after the initial presentation, she suffered multiple bouts of pancreatitis. Workup showed metastatic tumor to the pancreas which took a fatal course and lead to her death one year later. According to our knowledge, only 3 case reports of pancreatic metastasis from malignant phyllodes tumor have been reported in literature thus far.
Yameen Ali
Maternity and Children Hospital, KSA
Title: Spondylodiscitis challenging diagnosis in immune competent child: A case report
Time : 16:05-16:20
Biography:
Yameen Ali has completed his MBBS from King Faisal University, Saudi Arabia. He has obtained Saudi and Arab Board Certifi cate in General Pediatric, completed his Fellowship and Certifi ed in Pediatric Infectious Diseases in 2015 and Certifi cation in Infection Control (CIC) 2015. He is working as a Consultant in Pediatric and Pediatric Infectious Diseases and Head of Infection Control at Maternity and Children Hospital.
Abstract:
Spondylodiscitis, a combination of spondylitis and discitis, is an infection of the spine that involves the intervertebral disc and the vertebral body. Patients presented with little specifi c symptoms and suspicion for diagnosis is required. Th is report aimed to describe a female child patient with spondylodiscitis and to describe the diagnostic and therapeutic tools of such patient. Th is report recorded 2 year-old female child presented by fever, pain associated with standing and sitting and 10 days history of refusal to walk in Prince Sultan Medical City, Riyadh, Saudi Arabia. Laboratory investigations as well as hip and knee ultrasound showed no abnormalities. However, and hip and lower back Magnetic Resonance Image (MRI) showed evidence of abnormal hyper intensity with enhancement of the bone marrow involving the vertebral bodies and adjacent endplates of 5th lumber (L5) and 1st sacral (S1) vertebrae with involvement of intervertebral disc space and paravertebral soft tissue component. Spondylodiscitis was suggested in the child and conservative management by medical team of pediatrics and orthopedics consultant has immediately started. Th e treatment included antibiotics non-steroidal analgesia and physical rehabilitation. Th e patient was completely evolved from condition within days. MRI taken 6 weeks later showed signifi cant interval improvement of signs of spondylodiscitis and the girl has been seen in the clinic aft er 4 months from discharge in good condition. Spondylodiscitis has to be considered in young children with acute ambulation changes. Prompt diagnosis and treatment involving the entire multidisciplinary team is emphasized in order to improve the prognosis of such patients.
Sara Sohail
Jinnah Post Graduate Medical Centre Karachi, Pakistan
Title: Large invasive retroperitoneal paraganglioma mislabelled as hypertrophic obstructive cardiomyopathy
Time : 16:20-16:35
Biography:
Sara Sohail (main author) graduated from Dow University of Health Sciences (DMC) in 2010 at age of 23years ,internship in 2010-2011, cleared part 1 of Fellowship exam of Pakistan in 2011 at age of 24 and started postgraduate training at Jinnah Postgraduate Medical Centre in 2012, cleared part 1 and part 2 Membership exam of Royal College of Physicians UK in 2013. Due to knowledge, clinical skills and patient management received Scholarship by College of Physician and Surgeon Pakistan and currently completing remaining training in Ireland in Medicine on scholarship.
Abstract:
Paraganglioma originates from chromaffin cells of adrenal medulla and autonomic paraganglia, which are derived from the neural crest cells. Paragangliomas are half as common as pheochromocytomas; 69% occurring in head & neck, 22% in abdomen & pelvis and 10% in the thorax. About 70% paragangliomas are sporadic, 30% are hereditary having identifiable germline mutations of Succinate Dehydrogenase Enzyme (SDH). 13 years old male, hypertensive for 3 years, diagnosed as having Hypertrophic Obstructive Cardiomyopathy (HOCM) 1 year back, presented with complaints of altered consciousness and blurring of vision for 2 hours. On examination, blood pressure was 220/110 mmHg. He had a grade III intensity ejection systolic murmur at L lateral sternal border & grade II Pansystolic murmur at mitral area radiating to axilla. GCS was 5/15 with Rt plantar equivocal & Lt plantar up going. Hypertension was persistent in nature with acute elevation occurring especially in morning hours, controlled by intravenous vasodilators during acute elevations and alpha and beta blockers. There was no family history of hypertension. Hormonal workup revealed elevated urinary VMA levels of 68.3 mg/24 hours, suggestive of pheochromocytoma/paraganglioma. Ultrasound and CT-scan of abdomen confirmed large, retroperitoneal soft tissue mass, measuring 6.4×3.5 cm, involving R ureter and R renal vein, invading into the IVC with tumor thrombus with in it. His thyroid function tests, parathyroid hormone (PTH) and calcitonin, ultrasound neck and renal doppler were normal. Echo showed moderate asymmetrically hypertrophied LV and interventricular septum (non-obstructive). A percutaneous biopsy of mass had been done previously and had confirmed paraganglioma. A diagnosis of severe hypertension leading to hypertrophy of myocardium secondary to paraganglioma was made. Tumor was removed in total along with extension in the inferior vena cava from the entrance into R atrium up to R renal vein. Six months post-operative, patient remains well and has resumed his normal day to day activities. He remains normotensive and off all medications. His post-operative urinary VMA levels have also normalized (4 mg/hr). Repeat echocardiographic findings showed regression of changes with only mild asymmetrically hypertrophied left ventricle. This case report together with few others in literature indicates that HOCM like features can be induced by this tumor with complete or partial resolution of these features following successful tumor removal; this in contrast to classic HOCM which is a life-long irreversible disease.
Saba Hashim
Jinnah Postgraduate Medical Centre, Karachi, Pakistan
Title: Fluorosis, causing paraplegia.mutilating life
Time : 16:35-16:50
Biography:
Dr.Saba Hashim has completed MBBS from Dow Medical College Karachi and Postgraduate FCPS training in Internal Medicine from Jinnah Postgraduate Medical Centre.She is also doing MRCP from Royal College Of Physicians Of London
Abstract:
Fluorosis is thought to be rare in Pakistan but endemic in various parts of the world, especially in India and China. In Pakistan only a few cases have been reported from Thar, Sibbi and Manga Mandi with probability of fluorosis on MRI findings supported by high drinking water fluoride content. Neurological manifestations of skeletal fluorosis may vary from radiculo-myelopathy to neuropathy. A case of 26 years old female from Thul, Sindh, who presented with paraplegia is reported here. Her MRI showed extensive classical degenerative changes throughout the spine, consistent with fluorosis, leading to cord compression at multiple levels. No such case with confirmed fluorosis has been previously reported from Pakistan.
Shazma Khan
Aga Khan University Hospital, Pakistan
Title: Sporadic Creutzfeldt-Jakob disease: A case series from Aga Khan University Hospital
Time : 16:50-17:05
Biography:
Dr. Shazma Khan completed her M.B.B.S from Liaquat University of Medical & Health Sciences in 2007; followed by internship in 2008-9. Beginning her residency in 2011, she is currently working as a Neurology resident at Aga Khan University Hospital.
Abstract:
Creutzfeldt-Jakob disease (CJD) is a transmissible disease of the central nervous system caused by transformation of normal prion proteins into abnormal prions spontaneously and runs a rapid course till death once the disease sets in. This rare, degenerative disease is just one type of a group of prion diseases. Amply described in Western literature, Creutzfeldt-Jakob disease is scarcely reported in Asia. Whether this scarcity is because of missed diagnosis, unavailability of diagnostic procedures, under-reporting of diagnosed cases or because of actual rarity of the disease remains debatable. We found 4 reported cases of CJD in our literature of Pakistan; one each in 2007 and 2012 and two reported together in 2014. Key to diagnosis lies in interpreting the clinical data in light of work up including brain imaging, electroencephalogram, cerebrospinal fluid testing and biopsy of infected brain. The disease invariably progresses to demise and no treatment can arrest the process. We did a retrospective record review of Aga Khan University Hospital Neurology department from 1994 till 2015 and found 12 cases labeled as CJD. Based on the MRI-CJD European Consortium criteria, this case series will illustrate details of one biopsy proven definitive case and 5 probable CJD cases. To the best of our knowledge, we are reporting the biggest case series of this rare disease from Pakistan. With alternative diagnoses ruled out; brain MRI (excluding the biopsy proven case that had a CT brain done in 2001), electroencephalogram and testing of cerebrospinal fluid helped reach the diagnosis of CJD.
Meral Abualjadayel
King Abdulaziz University, KSA
Title: Case of renal oncocytoma in a 14 year old young lady
Time : 17:05-17:20
Biography:
Meral Abualjadayel completed her medical education from King Abdulaziz University, KSA. She is currently Pediatric Students Club Co-founder , Academic Education Unit President At King Abdul-Aziz University-faculty of Medicine. She also Volunteers in the Clinical skills mentoring program. She is the Organizer In "World Kidney Day" Event Held in King Abdulaziz University Hospital.
Abstract:
Renal oncocytoma was fi rst described by Zippelin 1942 as a malignant entity, however, Klein and valensi were able to demonstrate its benign characters in the year 1976. Th e current the World Health Organization have classifi ed renaloncocytomas as benign renal neoplasms in 2004. Renal oncocytoma is the second most common benign renal neoplasm after angiomyolipoma, comprising 3-7% of all renal tumors, usually occur during the seventh decade of life varying from 20 to 86 years of age with males predominance. Zhou defi ned renal oncocytoma as a benign epithelial neoplasm composed of round-to polygonal-cells with abundant mitochondriarich eosinophilic cytoplasm, thought to arise from the intercalated cells in the kidney. Th e size of the tumors varies from 0.6 to 14 cm(7). Unfortunately, most oncocytomas are very diffi cult to be diff erentiated from renal cell carcinoma both clinically and radio graphically. Development of renal oncocytoma in pediatric age group is very uncommon with no cases found within our review of the world literature. We report herein the fi rst case of renal oncoytoma in a 14 year old young lady.
Zahra Sarafraz
Shahid Sadoughi University of Medical Sciences, Iran
Title: Soft tissue mucormycosis in immunocompetent patient: A case report
Time : 17:20-17:35
Biography:
Zahra Sarafraz is currently a Resident in Otolaryngology Department of Shahid Sadoughi University of Medical Science, Iran. She has completed her MD and has 10 published articles and many presentations in different conferences such as ISCOMS, Esc-Berlin and AIMS. She has received “The Best Researcher Award” in the university (2014) and won “the Best Peer Reviewing Award” in the sixth SICOBAIR (2015).
Abstract:
Mucormycosis is considered the third most common invasive fungal disease aft er candidiasis and aspergillosis and all such diseases are important causes of morbidity and mortality. Mucormycosis almost always develops in patients with defects in their host defense and it is rare in healthy people. It can manifest in diff erent clinical presentations. Th e most frequent form is the rhinoorbito-cerebral mucormycosis. Cutaneous disease is the third most frequent manifestation of mucormycosis. In this study we investigate a 6-years-old immunocompetent boy complained of a large (15-20 cm) itching mass that had been enlarging slowly in his neck region (submental) for 4 months. CT scan revealed a large submental mass without abscess formation and biopsy showed mucormycosis in soft tissue specimen. Patient’s parents refused to surgery. His treatment and prognosis with liposomal amphotericin B are investigated in this study.
Dr Marzan
General Surgery training program in Naga City, Philippines
Title: Neopenis: The first total penectomy with total penile reconstruction using an anterolateral thight free flap for penile carcinoma in the Philippines
Time : 17:35-17:50
Biography:
Juan Carlos Bello Marzan has completed his MD from the University of Santo Tomas. He is the current Chief Resident of the Accredited Consortium in Education for Surgery, an accredited General Surgery training program in Naga City, Philippines. In 2015, he was invited as a speaker in the American College of Surgeons Clinical Congress, Chicago, IL, USA on his video on Superficial Parotidectomy.
Abstract:
"An absent or inadequate penis is a devastating condition with significant psychological, sexual, social and physical impact. Penile carcinoma with invasion of the shaft with an inadequate length is usually treated with Total Penectomy with Perineal Urethrostomy. In the Philippines, there is no literature that can trace back the roots of penile reconstructive surgery or even a single case ever performed. This is the first documented case of total penile reconstruction for penile carcinoma in the Philippines. This is a case of a 48 year-old Filipino male with Squamous Cell Carcinoma of the penis who underwent total penectomy and the first total penile reconstruction using an anterolateral thigh flap in the Philippines. We are presenting our technique of penile reconstruction using an anterolateral thigh flap. Elliptical incision is made around the base of the penis, dissection is commenced in the plane between the tunica albuginea and Buck fascia dorsolaterally and the dorsal vessels are ligated and divided. Corporeal bodies are sharply transected and the urethra is divided at the same level. The corpora are then closed with interrupted horizontal mattress sutures. The dissection started, identifying the descending branch of the lateral circumflex femoral artery to its origin and then the lateral cutaneous nerve of the left thigh was identified at the proximal border of the flap and dissected 5 cm in length. During the dissection, two perforators within the flap were identified and maintained. The flap was harvested as an island flap based on both perforating vessels and the pedicle was dissected up to its origin. Urethra and neopenis was constructed using tube over tube technique. Inset of the neopenis was then made thru tunneling underneath the femoris muscle through an incision in the left groin region. Flap was then sutured to the periosteum of the pubic region. The neourethra was anastomosed to the remaining corpus spongiosum with adequate spatulation using chromic 4-0. Flap donor site closure was done with split thickness skin graft harvested from the hypogastric area. At present patient is able to urinate in a standing position. "
Jumana Amir
University of Dammam Medical School, KSA
Title: Mesenchymal hamartoma presenting as vocal cord paralysis: A case report and review of literature
Time : 17:20-17:55
Biography:
Jumana Amir is currently working as a Intern at University of Dammam Medical School, KSA
Abstract:
Hamartoma of the larynx is a rare benign developmental anomaly that must be distinguished from other neoplastic and non-neoplastic lesions of the larynx. Most cases come to medical attention due to symptoms related to airway obstruction. Only one case is reported in literature where the lesion was associated with vocal cord paralysis. We herein, present a 68 years old woman who was admitted to the hospital with hoarseness, dysphagia, and left vocal cord paralysis. A laryngeal lesion was identified and on biopsy was diagnosed to be mesuj
Shazma Khan
Aga Khan University Hospital, Pakistan
Title: Methicillin-resistant Staphylococcus aureus: Case report of acute sinusitis with orbital extension in a pregnant lady
Time : 17:20-17:55
Biography:
Shazma Khan has completed her MBBS from Liaquat University of Medical & Health Sciences in 2007 followed by Internship from 2008-2009. She is currently working as a Neurology Resident at Aga Khan University Hospital, Pakistan.
Abstract:
Recognized since 1960s, methicillin-resistant Staphylococcus aureus (MRSA) has increasingly been recognized as a cause of soft tissue infections. Previously believed to be transmitted solely via health care systems in immunocompromised hosts, it is now believed that diff erent strains are responsible for spread of infection in immunocompetent individuals in community. Th is form is referred to as community acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) which is mainly associated with soft tissue abscesses and cellulitis. Acute sinusitis due to MRSA can be one of the deadest presentations of this infection as it can quickly lead to orbitocranial involvement with complications including blindness, brain abscess and death. Seriousness of MRSA infection increases manifold when the infection occurs in pregnant women. While still not known in developing countries, the prevalence of MRSA colonization in pregnant women in western world is stated to be 0.5-4%. Early suspicion of infection is the key to better prognosis. Appropriate antibiotics should be started without delay and early drainage of abscess, if any, should be the target. Delay in treatment, medical or surgical, may lead to serious consequences including death. We present here the case of a 34-year-oldlady who was 31 weeks’ pregnant and presented with one day history of severe right sided headache. She was found to have acute sinusitis that involved right orbit in less than 24 hours of presentation. A diagnosis of sinusitis secondary to CA-MRSA was made. Promptly managed with intravenous antibiotics and drainage of maxillary sinus abscess, the patient made remarkably complete recovery without any complications.
Deanne Soares
Royal Prince Alfred Hospital, Australia
Title: Papillary renal cell carcinoma seeding along a percutaneous biopsy tract
Biography:
Deanne Soares is a Senior Surgical Resident at Concord Repatriation General Hospital in Sydney, Australia. She has completed her Master of Surgery from The University of Sydney and a Master of Health Leadership and Management from the University of Wollongong. She is currently engaged in multiple research projects in the fi elds of surgery and training and education.
Abstract:
The use of percutaneous biopsies is useful in the diagnosis and management of renal masses with a complication rate of <0.01%. However, a potential hazard of this is tract tumor seeding but this is so rare in renal cell carcinoma (RCC) that its frequent use in the assessment of indeterminate renal masses has been justifi ed. We report a case of tumor seeding caused by percutaneous biopsy of a papillary renal cell carcinoma detected on pathological assessment of the partial nephrectomy specimen in a 50 year old male. Literature review found that up until 1991, there were only 5 reported cases of RCC tract seeding and in 2013 there were a further 3 cases reported. In general, tract seeding will relate to the amount of disruption of the tumor capsule (needle caliber, number of punctures), pressure of egress at the puncture site (for example, cystic masses or escaping hematoma), whether tumor cells are dropped from the needle on its withdrawal (failure to maintain negative pressure, burred needle tip) and the ability of tumor cells to survive when deposited into a scar. Th is is one of only a few contemporary case reports of RCC seeding along a percutaneous biopsy tract. Whilst this complication is so rare that it does not warrant a need to cease the use of percutaneous biopsy of renal masses, it certainly highlights the possibility of tract seeding as a potential hazard. As such, certain considerations such as appropriate patient selection, the use of correct equipment and suitable biopsy technique, should be made to minimize the risk of this complication
Tesnim Besbes
University Hospital of Sahloul Sousse, Tunisia
Title: Takayasu arteritis presenting as preeclampsia and postpartum persistent high blood pressure: Case report
Biography:
Working as an Associate Professor
Abstract:
Takayasu arteritis is a chronic inflammatory disease and a common etiology for abdominal aortic coarctation. Hypertension is a frequent clinical manifestation and treatment is warranted to prevent major complications. This is a case of a 29-year-old woman with solitary kidney presenting with preeclampsia and diagnosed with Takayasu arteritis. Lesions included abdominal aortic coarctation, poststenotic aneurysm and severe renal artery stenosis. The patient was managed by surgical approach, postoperative period was uneventful and symptoms improved dramatically.
Narjiss Akerzoul
Mohammed V University, Morocco
Title: The use of free fibula flap in the mandibular reconstruction in case of ameloblastoma
Biography:
Resident Research Assistant at Department of Oral Surgery, Consultation Center of Dental Treatment of Rabat, Mohammed V University of Rabat-Morocco, School of Dental Medicine
Abstract:
Introduction: The ameloblastoma is a rare odontogenic tumor of the oral cavity. It affects more the mandible than the maxilla and has a predilection for the posterior region. Although this tumor is benign, its behavior is locally aggressive and requires the most often surgical resection margin. Clinical Observation: A young woman aged 28 has consulted the service of Surgical Dentistry of Rabat, complaining of right mandibular swelling lasting for eight months. Panoramic radiography revealed the presence of a multi-geodic picture at the right hemi-mandible. A biopsy was performed at the level of the lesion and entered the presence of aameloblastoma. The patient was subsequently sent to the Maxillofacial Surgery Service of the Hospital of Specialties of Rabat. Two teams, one of maxillofacial surgery and other vascular surgery collaborated to produce a hemi-mandibulectomy poses with a graft of the fibula. Discussion: The indication of radical or conservative treatment should be guided by the anatomical location of the lesion, the radiological aspect and especially macroscopic intraoperative. Conservative treatment is carried out for non extensive lesions with the assurance of a future clinical monitoring. Bone resection with or without immediate reconstruction is needed in extended forms breaking cortical bone, the periosteum and soft tissue invasiveness. The free fibula flap was the preferred graft for oromandibular reconstruction because of its versatility and the consistency in the size of the fibula bone and stability. The free fibula flap allows skin palette to be obtained that is up to 25 cm long and 5 cm wide. The fibula periosteal vascularization and thus can withstand multiple osteotomies without compromising significantly, when the periosteum is left set. The free graft of the fibula can be considered a reliable graft with low morbidity and also adapted for future dental rehabilitation.
Sanjeev Gupta
Banarsidas Chandiwala Institute of Physiotherapy, New Delhi, India
Title: Applications of IoT in Physiotherapy
Biography:
Sanjeev Gupta, is graduate from National Institute for the Orthopaedically Handicapped Calcutta, India; specializes in orthopaedics (MPT Ortho) Uttranchal University, India. He has been associated several premiere physiotherapy institutions in one or more capacities as Director, Principal, Consultant & Academician. He is chief editor of “The Physiotherapy Post†a registered Journal of Physiotherapy. He has supervised many Researchers and has contributed to several publications (including Cerebrovascular Diseases, S. Karger AG – Medical and Scientific Publishers, Switzerland). He has edited and reviewed many research publications. He has been product consultant with apex manufacturers in field of physiotherapy. He has invented a novel tool 'Bodygraph' for physiotherapy / orthopaedic assessment
Abstract:
The presentation has two parts (Discussion & Case Studies) besides introduction to the concept of IoT (Internet of Things). Initially it unveils the scope and potential of this IT based technology in the different domains of Physiotherapy. It discusses scope of Big Data Analysis (BDA), Information Communication Technology (ICT) and Ambient Intelligence (AI). In the later part of the presentation novel techniques to utilize existing IoT based gadgets & applications in the field of physiotherapy are showcased. The portion unfolds mobile to gaming all into the physiotherapeutic applications as enabler or adjunct. Late portion of the portion proposes game changing IoT possibilities in the dimensions not limited to prevention, treatment delivery- monitoring-modulation and EDP related issues. In-between presentation also touches local experiences and challenges faced in adoption of such technology. The presentation will also include a case study: Application of IoT in an Indian Context, an experience based roadmap to future.
Kapil
D Y Patil Dental School, India
Title: Assessment of Indian classical music in reducing pain during dental infiltration procedure.
Biography:
Kapil Kshirsagar has completed his Masters in Oral and Maxillofacial Surgery in 2010 from Dr. D Y Patil University. He is currently working as an Associate Professor at D Y Patil Dental School, Charoli Bk, Pune, India. He has published 12 papers in reputed journals.
Abstract:
In the treasury of human experience, no emotion leaves as vivid an imprint on man’s memory as one characterized by pain; a painful experience being one that is not only unforgettable, but also one that produces changes within that individual’s psyche as regards future painful experiences. Dental treatment has long been associated in mind of the patient with pain. Although local anesthetics work to prevent pain, the perception among all too many people is that the administration of local anesthetics is painful. The alleviation of pain therefore comprises one of the most important and satisfying duties of one engaged in health services. As an auditory stimulus, music activates a number of neurotransmitters and it can divert feelings of pain, fear and anxiety, thereby allowing people to gain more positive perceptual experiences. Indian music has a long tradition of thousands of years. It has been shown to be soothing and effective in providing relief in painful conditions such as arthritis. Also Indian classical music has soothing qualities that change the mood of dejected, depressed and distressed individuals facing stressful situations. Raaga-‘Todi’ was used in the study uniformly as the prism of raaga-‘Todi’ (from ecstasy to frolic to pathos to melancholy) has the capacity to refract every conceivable human emotion. This study aims to assess the efficacy of Indian classical music in reducing pain during local anesthetic infiltration.
Satish Anumula
Swami Vivekananda Yoga Anusandhana Samsthanam (s-vyasa) University, India.
Title: Reduction of jaw (t mj) dislocation with taping technique: A case report.
Biography:
Dr.satish kumar anumula has completed his bachelor of physiotherapy (bpt) from Dr.NTR university of health sciences, Vijayawada, Andhra Pradesh, India and Msc in applied sports and exercise science at the age of 24 years from Unversity of Wolverhampton, United kingdom. He is the Assistant Professor& Chief of Physiotherapy department at Swami Vivekananda Yoga Anusandana Samsthanam, a deemed University, and the world class yoga university in the globe
Abstract:
The facial area is one of the most frequently injured areas of the body and the mandible is one of the most common maxillofacial bones dislocates because of its prominent position on the face, the powerful muscle attachments and the lack of support. Dislocations occur when two bones that originally met at the joint detaches. If the jaw is dislocated, it may cause severe headache, inability to concentrate apart from pain and incomplete opening of the mouth. Taping a very popular treatment for several health conditions over the last decade; Kinesio Tape is thinner and more elastic than conventional tape which is hypothesized to allow greater mobility and skin traction. A male aged 35 years was admitted to arogyadhama with pain in the face and inability to open his mouth from past 06 months. He has complained of constant mild pain in the face in front of the left ear that would get aggravated after eating solid food. We suspected Jaw dislocation and got an X-ray of the jaw and that showed grade 1 anterior dislocation. We planned physiotherapy treatment aimed at pain relief (ultrasound therapy), reduction of the dislocation (taping technique) and strengthening the jaw muscles (exercises). After 02 weeks of this therapy check X-ray of the jaw was taken which showed correction of the dislocation with normal appearance of the TMJ. The participant felt better, the pain has decreased and was able to open the mouth wider than before.
Bushra Tahir
Riphah International University, Islamabad. Pakistan
Title: Risk factors assessment for dry sockets: A logistic regression analysis study
Biography:
Bushra Tahir Khan has completed her BDS at the age of 22 years from Islamic International Dental College, Riphah International University, Pakistan
Abstract:
Aim: To investigate the effect of age, gender, address, type of extraction, type of operator and the arch of the tooth involved in the occurrence of dry sockets. A secondary aim of the study was to calculate the incidence of dry sockets in Islamabad, Pakistan Materials and Methods: This study was conducted in the Oral and Maxillofacial Surgery Department at Islamic International Dental Hospital from April 2013 till May 2013. Data was collected for any complaints of dry socket following tooth extractions, by means of a structured questionnaire. All patients above 18 years of age were included. Mean and standard deviation were calculated for age. Frequencies were calculated for gender, address, operator type, arch and the outcome (occurrence of dry socket). A binary logistic regression analysis was conducted to establish a risk model to relate the variables with the occurrence of dry socket. Pearson’s Chi Square test was applied to assess the frequency of occurrence with age. Results: Out of 1670 patients, 1563 adults fulfilled the inclusion criteria. 80 patients reported with dry socket, the incidence being 5.12%. Logistic regression analysis showed a statistically significant association between age and the development of dry socket (OR=0.953, 95% CI=0.926 – 0.961). None of the other factors had a significant association with the occurrence of dry sockets. Conclusion: A significant association exists between patient’s age and development of dry socket. An inverse relationship was seen between the increase in age and occurrence of dry socket. No such association is seen between patient gender, address of the patient, location of the tooth, operator and extraction type.
Abraham Getchew
Ayder Referral Hospital, Ethiopia
Title: Magnitude and associated factors of atopic dermatitis among children In Ayder Referral Hospital, Mekelle, Ethiopia
Biography:
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Abstract:
Background: Atopic Dermatitis (AD) is now a day’s increasing in prevalence globally. A Prevalence of 5- 25% have been reported in different country. Even if its prevalence is known in most countries especially in developing countries there is scarcity with regard to prevalence and associated risk factors of AD among children in Ethiopia settings. The aim of this study was to determine the magnitude and associated factors of atopic dermatitis among children in Ayder referral hospital, Mekelle, Ethiopia. Methods: A facility-based cross-sectional study design was conducted among 477 children aged from 3 months to 14 years in Ayder referral hospital from July to September,2014. A systematic random sampling technique was used to identify study subjects. Descriptive analysis was done to characterize the study population. Bivariate and multivariate logistic regression was used to identify factors associated with AD. The OR with 95% CI was used to show the strength of the association and a P value < 0.05 was used to declare the cut of point in determining the level of significance. Results: Among the total respondents, 237(50.4%) were males and 233 (49.6%) were females. The magnitude of the atopic dermatitis was found to be 9.6% (95% CI: 7.2, 12.5). In multivariate logistic regression model, those who had maternal asthma (AOR: 11.5, 95%CI:3.3-40.5), maternal hay fever history (AOR: 23.5, 95%CI: 4.6-118.9) and atopic dermatitis history (AOR: 6.0, 95%CI:1.0-35.6), Paternal asthma (AOR: 14.4, 95% CI:4.0-51.7), Paternal hay fever history (AOR: 13.8, 95%CI: 2.4-78.9) and personal asthma (AOR: 10.5, 95%CI:1.3-85.6), and hay fever history (AOR: 12.9, 95%CI:2.7-63.4), age at three months to 1 year(OR: 6.8, 95%CI: 1.1-46.0) and weaning at 4 to 6 months age (AOR: 3.9, 95% CI:1.2-13.3) were a significant predictors of atopic dermatitis. Conclusion: In this study the magnitude of atopic dermatitis was high in relation to other studies conducted so far in the country. Maternal, paternal, personal asthma, hay fever histories, maternal atopic dermatitis history, age of child and age of weaning were independent predicators of atopic dermatitis. Hence, the finding alert a needs of strengthening the national skin diseases prevention and control services in particular in skin care of children related to atopic dermatitis and others. In avoiding early initiation of supplementary feeding specially with personal and families with atopic problem needs further attention of prevention activities. Keyword: Atopic dermatitis, cross sectional study, magnitude, institutional based study. [01] Abraham Getachew Kelbore, Mekelle University, postgraduate in Tropical Dermatology, Mekelle, North Ethiopia [02] Workalemahu Alemu, Mekelle University, Dermatovenereology department, Mekelle, North Ethiopia [03] Ashenafi Shumye, Mekelle University, public health department, Mekelle, North Ethiopia [04] Sefonias Getachew, Addis Ababa University, school of Public Health, Addis Ababa, Ethiopia
Lambert Mugabo
DelAgua Health Rwanda Implementation Ltd, Rwanda
Title: Enhancement of training completion rate in rural Rwanda: innovations into an introduction to research course
Biography:
Lambert Mugabo holds a bachelor’s degree in Applied Statistics from National University of Rwanda. Following the completion of his undergraduate studies, He joined Digital Opportunity Trust-Rwanda where, through training on computer, business, and life skills; built capacities of women and youth at grassroots level to enable them transform their lives. Over the last 3 years Lambert’s career was mainly characterized by research work. He contributed to various research projects at different institutions such as East African Community Secretariat and Center for Development Research. In 2013 He obtained a Global Health Corps fellowship and worked as Research Fellow at Partners In Health-Rwanda where he supported research capacity building through developing a web-based research course and conducted research projects whose resulted were published in international peer-review journals. He currently works as Education Program Coordinator at DelAgua Health Rwanda Implementation Limited, where he coordinates the implementation of the training program and research activities
Abstract:
Introduction to research methods course developed by the research department at Partners In Health, Rwanda since 2013 contributes to laying a solid foundation for health research capacity building of health workforce and promotes the consumption of health research. To address the challenge of incompletion of the training observed during its first offering due to competing work responsibilities and attrition of health workers, innovations have been made into its second offering. The duration of the training was reduced from 11 months to just 2 ½ whereby a session was run on weekly basis instead of monthly basis. In addition, a web-based version of the course was developed to make the course flexible and enhanced comprehension of the course materials. Though innovations into the course increased the cost due to the introduction of technology and prompted a decrease of enrollment rate, on the other side, completion rate rose to 95% in the second offering compared to 48% in its previous offering and development of web-based course offers an opportunity to reach a wider audience. Further, there is a need to find suitable technologies for resource-limited settings that do not have good internet