Clinical and Medical Case Reports

Large cell neuroendocrine carcinoma (LCNEC) is a rare entity usually arising from a pulmonary origin. Unfortunately, due to a lack of clinical trials, there is no defi ned approach for the treatment of these cancers. To date there have only been two reported cases of LCNEC originating from the base of tongue. In this case report we discuss the presentation, management and disposition of a patient diagnosed with LCNEC originating from the base of tongue, with a review of the current literature