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Pariessa

Pariessa

University of Santo Tomas Hospital, Philippines

Title: Post-Varicella acute demyelinating polyradiculoneuropathy in a 51-Year old filipino male

Biography

Biography: Pariessa

Abstract

Background: Primary Varicella zoster infection is commonly observed in school-aged children. There are increasing reports of adults being affected. Varicella zoster infection has a myriad of clinical complication. The rarer of these complications is Guillan Barre syndrome (GBS) or acute inflammatory demyelinatimg polyradiculoneuropathy (AIDP), with less than 50 cases in reported literature. Objectives: Our aim is to highlight a rare case of post-varicella infection GBS happening in an adult. Methods: This is a case report with a concise history and adequate ancillary work-up. Results: We report a case of a 51-year-old Filipino male who presented with weakness and numbness of both upper and lower extremities two weeks after a primary varicella infection. CSF analysis for this patient showed elevation of CSF protein (69 mg/dl). CSF Varicella virus IgG was 1.8 mIU/ml and IgM was at 1 mIU/ml. Nerve conduction velocity studies showed delayed latencies or absent response, prolonged conduction velocities or absent response, temporal dispersion, and partial conduction block at both median, ulnar, tibial and peroneal nerves. Conclusion: The objective finding in this case as well as the clinical history is indicative of a demyelinating sensorimotor polyneuropathy after a varicella infection.